Thygesons Superficial Punctate Keratopathy

Archive for Histology

The Morphology of Thygeson’s Superficial Punctate Keratitis Lesions

Thygeson’s Superficial Punctate Keratitis affects cells that lie within the intraepithelial region of the cornea.  At an individual level, each entity is small, round, light reflecting cells around 10-15 μm in diameter).  The disease can present itself as a single cell entity or cells clustered in small groups or they can aggregate into lesions that […]

Histology of Thygeson’s Superficial Punctate Keratitis

Thygeson’s Superficial Punctate Keratitis, TSPK, or Thygeson’s Superficial Punctate Keratopathy has an unknown cause and this mystery has baffled the global medical community for over 60 years. The histology of TSPK has shown that intracellular and intercellular edema at the epithelial level are commonly found in TSPK patients.  Sixteen TSPK patients were inspected with a […]

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