Thygesons Superficial Punctate Keratopathy

HLD DR3 antigen affects response to Thygeson’s Superficial Punctate Keratitis

In 1981, Richard W. Darrell, MD, reviewed literature relating to TSPK and its association with a histocompatibility antigen HLA DR3.  Both HLA D and HLA DR antigens are associated with the immune response genes, and HLD DR3 antigen may interfere with the immune response of patients of Thygeson’s Superficial Punctate Keratitis to endogenous and exogenous […]

Topical Therapy in Thygeson’s Superficial Punctate Keratitis

When someone is affected by the severity of Thygeson’s Superficial Punctate Keratitis or in any of its signs, symptoms, or following remission, various therapies are considered depending on the severity of the disease at the time the patient presents to the eye care specialist. Where a patient presents with a mild case, then they may […]

Corticosteroids and Cyclosporine Treatments for Thygeson’s SPK

Studying the opacities or lesions created by Thygeson’s SPK, also known as Thygeson’s Superficial Punctate Keratopathy, Thygeson’s Superficial Punctate Keratitis and TSPK, shows a crystalline appearance on the corneal surface that resemble snowflakes.  They vary in location and fluctuate in numbers even on a weekly basis during a flare up of the condition affecting the […]

Thygeson’s Superficial Punctate Keratitis Prognosis

Thygeson’s Superficial Punctate Keratitis prognosis means that some patients suffering with Thygeson’s SPK are surprised to learn that the outcome is usually manageable. The disease often appears, and then goes into remission only to reappear again. That scenario may happen for a period of four years in the average patient. In some rare cases Thygeson’s […]

Thygeson’s Superficial Punctate Keratitis (TSPK) Treatment Complications

The good news is that Thygeson’s Superficial Punctate Keratitis (TSPK) complications are far fewer than when the disease was first presented to the medical community in 1950.There are irritating symptoms such as chronic dry eye, burning sensations that come and go in the eyes, a high degree of sensitivity to bright lights or even sunshine […]

Followup Care for Thygeson’s Superficial Punctate Keratitis Patients

Thygeson’s Superficial Punctate Keratitis (TSPK) patients will find out that the cause of this disease has eluded the medical community around the world for over 60 years.  During that over half a century there has been many experiments and case studies conducted to determine how to best diagnose, treat, and provide followup care for TSPK […]

Thygeson’s Superficial Punctate Keratitis Medication

There are different types of eye drops commonly used for the treatment of the symptoms of Thygeson’s Superficial Punctate Keratitis.  No Thygeson’s Superficial Punctate Keratitis medication is currently available that will cure the eye condition. Fluorometholone is used to reduce inflammation and neovascularization in the cornea while limiting the movement of polymorphonuclear leukocytes and reversing […]

Histology of Thygeson’s Superficial Punctate Keratitis

Thygeson’s Superficial Punctate Keratitis, TSPK, or Thygeson’s Superficial Punctate Keratopathy has an unknown cause and this mystery has baffled the global medical community for over 60 years. The histology of TSPK has shown that intracellular and intercellular edema at the epithelial level are commonly found in TSPK patients.  Sixteen TSPK patients were inspected with a […]

Thygeson’s Superficial Punctate Keratitis Laboratory Studies

The truth is that Laboratory Studies regarding the cause of Thygeson’s Superficial Punctate Keratitis (TSPK) have failed to determine the cause or causes of this disease.  It is reported that medical personnel can try culturing the flora when there is active inflammation of the cornea, but it will not affect the management, diagnosis, or treatment […]

Differential Diagnoses Pertaining to Thygeson’s Superficial Punctate Keratitis

The cause or causes of Thygeson’s Superficial Punctate Keratitis (TSPK) continue to elude the medical community. Differential diagnoses pertaining to TSPK include many candidates. Many people have experienced pink eye or what is known as conjunctivitis that occurs when the eyelid membrane is infected and swells.  Conjunctivitis is sometimes diagnosed when the problem could really […]

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